MolNFT v1 · #146909 · protein

Structure of human cytochrome P450 1A1 with bergamottin

6DWM: “Structure of human cytochrome P450 1A1 with bergamottin”. X-ray diffraction, 3 ligands (HEM, HJJ, CPS). MolNFT v1 #146909 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6DWM
Type: protein
Length: 1,874 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P04798
Ligands: HEM, HJJ, CPS

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	470	—	P04798
B	—	protein	476	—	P04798
C	—	protein	464	—	P04798
D	—	protein	464	—	P04798

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains A, B, C, D
HJJ · 4-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3, 2-g][1]benzopyran-7-one · ligand · 4 copies · chains A, B, C, D
CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · ligand · 2 copies · chains A, D
GOL · Glycerol · additive · 2 copies · chains B, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6DWM · Structure of Human Cytochrome P450 1A1 with Bergamottin · the same entry in another collection · chain D against D, TM-score 1.00
P04798 · AlphaFold monomer V2.0 prediction for cytochrome P450 1A1 (P04798) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04798
Elsewhere: RCSB PDB 6DWM · PDBe 6DWM · UniProt P04798

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