MolNFT v1 · #146769 · protein

Otu domain of FAM105A

6DRM · Inactive ubiquitin thioesterase FAM105A: “Otu domain of FAM105A”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #146769 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6DRM
Type: protein
Length: 270 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Inactive ubiquitin thioesterase FAM105A
UniProt: Q9NUU6
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 59% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Inactive ubiquitin thioesterase FAM105A	protein	270	59% helix, 10% strand	Q9NUU6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.33	0.74	18	empty

Compared structures

6DRM · OTU domain of Fam105A · the same entry in another collection · chain A against A, TM-score 1.00
Q9NUU6 · AlphaFold monomer V2.0 prediction for inactive ubiquitin thioesterase otulinl (Q9NUU6) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NUU6
Elsewhere: RCSB PDB 6DRM · PDBe 6DRM · UniProt Q9NUU6

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