MolNFT v1 · #146760 · protein

Crystal structure of the yoph PTP1B wpd loop chimera 3 ptpase bound to tungstate

6DRB · Targeted effector protein: “Crystal structure of the yoph PTP1B wpd loop chimera 3 ptpase bound to tungstate”. X-ray diffraction, 1 ligand (WO4), 1 pocket (best druggability 0.48). MolNFT v1 #146760 on GenesisL1: 3D structure…

PDB: 6DRB
Type: protein
Length: 278 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Targeted effector protein
UniProt: O68720
Ligands: WO4
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Targeted effector protein	protein	278	37% helix, 19% strand	O68720

Ligands and binding sites

WO4 · Tungstate(vi)ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	147	0.48	0.78	21	empty

Compared structures

6DRB · Crystal Structure of the YopH PTP1B WPD loop Chimera 3 PTPase bound to tungstate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O68720
Elsewhere: RCSB PDB 6DRB · PDBe 6DRB · UniProt O68720

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