MolNFT v1 · #14676 · protein
Crystal structure of a phopholipase A2 monomer with isoleucine at second position
1MH8 · Phospholipase A2: “Crystal structure of a phopholipase A2 monomer with isoleucine at second position”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #14676 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1MH8
- Type
- protein
- Length
- 119 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phospholipase A2
- EC
- 3.1.1.4
- UniProt
- P60043
- Pockets
- 1 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phospholipase A2 (EC 3.1.1.4) | protein | 119 | 48% helix, 11% strand | P60043 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.50 | 0.80 | 19 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 1MH8 · Crystal Structure of a Phopholipase A2 Monomer with Isoleucine at Second Position · the same entry in another collection · chain A against A, TM-score 1.00
- P60043 · AlphaFold monomer V2.0 prediction for basic phospholipase A2 1 (P60043) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60043
- Elsewhere: RCSB PDB 1MH8 · PDBe 1MH8 · UniProt P60043
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