MolNFT v1 · #146750 · protein

Actinobacillus ureae class id ribonucleotide reductase alpha subunit

6DQX · Ribonucleoside-diphosphate reductase, alpha chain: “Actinobacillus ureae class id ribonucleotide reductase alpha subunit”. X-ray diffraction, 2 ligands (MG, CL), 4 pockets (best druggability 0.61). MolNFT v1 #146750 on GenesisL1: 3D…

PDB: 6DQX
Type: protein
Length: 520 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonucleoside-diphosphate reductase, alpha chain
EC: 1.17.4.1
UniProt: E8KJ17
Ligands: MG, CL
Pockets: 4 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribonucleoside-diphosphate reductase, alpha chain (EC 1.17.4.1)	protein	520	48% helix, 10% strand	E8KJ17

Ligands and binding sites

MG · Magnesium ion · metal · 2 copies · chains A
CL · Chloride ion · ion · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 4 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	340	0.61	0.78	42	CL
2	101	0.41	0.77	26	empty
3	75	0.37	0.76	16	empty
4	80	0.35	0.76	17	empty

Compared structures

6DQX · Actinobacillus ureae class Id ribonucleotide reductase alpha subunit · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E8KJ17
Elsewhere: RCSB PDB 6DQX · PDBe 6DQX · UniProt E8KJ17

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