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MolNFT v1 · #146565 · protein

Crystal structure of IGLON5/NEGR1 heterodimer

6DLD: “Crystal structure of IGLON5/NEGR1 heterodimer”. X-ray diffraction, 3 ligands (NAG, BMA, MAN). MolNFT v1 #146565 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6DLD
Type
protein
Length
1,056 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A6NGN9, Q7Z3B1
Ligands
NAG, BMA, MAN

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein273—A6NGN9
B—protein247—Q7Z3B1
C—protein267—A6NGN9
D—protein269—Q7Z3B1

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 17 copies · chains A, D, B, C
  • BMA · beta-D-mannopyranose · sugar
  • MAN · alpha-D-mannopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6DLD · Crystal structure of IgLON5/NEGR1 heterodimer · the same entry in another collection · chain D against D, TM-score 1.00
  • Q7Z3B1 · AlphaFold monomer V2.0 prediction for neuronal growth regulator 1 (Q7Z3B1) · a predicted model of the same protein · chain B against A, TM-score 0.93
  • A6NGN9 · AlphaFold monomer V2.0 prediction for iglon family member 5 (A6NGN9) · a predicted model of the same protein · chain C against A, TM-score 0.86

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