MolNFT v1 · #146498 · protein
Crystal structure of human bromodomain-containing protein 4 (BRD4) bromodomain with MS645
6DJC: “Crystal structure of human bromodomain-containing protein 4 (BRD4) bromodomain with MS645”. X-ray diffraction, 1 ligand (CF6). MolNFT v1 #146498 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6DJC
- Type
- protein
- Length
- 262 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60885
- Ligands
- CF6
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 131 | — | O60885 |
| B | — | protein | 131 | — | O60885 |
Ligands and binding sites
- CF6 · N,N'-(decane-1,10-diyl)bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide} · ligand · chains A
- EDO · 1,2-ethanediol · additive · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6DJC · Crystal structure of human Bromodomain-containing protein 4 (BRD4) bromodomain with MS645 · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 6DJC · PDBe 6DJC · UniProt O60885
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