MolNFT v1 · #146265 · protein
Mycobacterium marinum cytochrome P450 CYP150A6 in the substrate-free form
6DCD · Cytochrome P450 150A6 CYP150A6: “Mycobacterium marinum cytochrome P450 CYP150A6 in the substrate-free form”. X-ray diffraction, 1 ligand (HEM), 3 pockets (best druggability 0.79). MolNFT v1 #146265 on GenesisL1: 3D structure…
- PDB
- 6DCD
- Type
- protein
- Length
- 406 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450 150A6 CYP150A6
- UniProt
- B2HFD6
- Ligands
- HEM
- Pockets
- 3 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 150A6 CYP150A6 | protein | 406 | 50% helix, 11% strand | B2HFD6 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 516 | 0.79 | 0.86 | 61 | HEM |
| 2 | 111 | 0.53 | 0.82 | 23 | empty |
| 3 | 99 | 0.36 | 0.74 | 16 | empty |
Compared structures
- 6DCD · Mycobacterium marinum cytochrome P450 CYP150A6 in the substrate-free form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2HFD6
- Elsewhere: RCSB PDB 6DCD · PDBe 6DCD · UniProt B2HFD6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.