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MolNFT v1 · #146185 · protein

JAK3 with cyanamide CP10

6DA4: “JAK3 with cyanamide CP10”. X-ray diffraction, 1 ligand (G4V). MolNFT v1 #146185 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6DA4
Type: protein
Length: 281 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P52333
Ligands: G4V

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	281	—	P52333

Ligands and binding sites

G4V · (Z)-1-{2,2-difluoro-6-[5-(2-methoxyethyl)-7H-pyrrolo[2, 3-d]pyrimidin-4-yl]-2,3-dihydro-4H-1,4-benzoxazin-4-yl}methanimine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6DA4 · JAK3 with Cyanamide CP10 · the same entry in another collection · chain A against A, TM-score 1.00
P52333 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase JAK3 (P52333) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52333
Elsewhere: RCSB PDB 6DA4 · PDBe 6DA4 · UniProt P52333

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