MolNFT v1 · #146053 · protein

The structure of atzh: a little known member of the atrazine breakdown pathway

6D63: “The structure of atzh: a little known member of the atrazine breakdown pathway”. X-ray diffraction, 1 ligand (6JN), 19 pockets (best druggability 0.73). MolNFT v1 #146053 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6D63
Type: protein
Length: 1,469 residues
Chains: 12
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Atzh
UniProt: A0A0V8SMU2
Ligands: 6JN
Pockets: 19 · best druggability 0.73

Structure

x-ray diffraction · 12 distinct chains · 30% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Atzh	protein	127	31% helix, 41% strand	A0A0V8SMU2
B	Atzh	protein	128	28% helix, 41% strand	A0A0V8SMU2
C	Atzh	protein	125	31% helix, 40% strand	A0A0V8SMU2
D	Atzh	protein	115	31% helix, 43% strand	A0A0V8SMU2
E	Atzh	protein	119	29% helix, 44% strand	A0A0V8SMU2
F	Atzh	protein	126	31% helix, 41% strand	A0A0V8SMU2
G	Atzh	protein	115	31% helix, 43% strand	A0A0V8SMU2
H	Atzh	protein	121	32% helix, 41% strand	A0A0V8SMU2
I	Atzh	protein	123	29% helix, 42% strand	A0A0V8SMU2
J	Atzh	protein	129	30% helix, 42% strand	A0A0V8SMU2
K	Atzh	protein	120	29% helix, 42% strand	A0A0V8SMU2
L	Atzh	protein	121	29% helix, 41% strand	A0A0V8SMU2

Ligands and binding sites

6JN · 3-oxopentanedioic acid · ligand · 3 copies · chains A, B, J

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

19 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	641	0.73	0.80	83	6JN
2	699	0.70	0.77	58	empty
3	371	0.63	0.78	58	6JN
4	217	0.61	0.81	34	empty
5	97	0.60	0.88	21	6JN

Interfaces

19 interfaces between chains.

A–B · 1578 Å² buried · 24 hydrogen bonds · protein-protein
C–D · 1530 Å² buried · 22 hydrogen bonds · protein-protein
K–L · 1524 Å² buried · 24 hydrogen bonds · protein-protein
G–H · 1492 Å² buried · 23 hydrogen bonds · protein-protein
E–F · 1491 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

6D63 · The structure of AtzH: a little known member of the atrazine breakdown pathway · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0V8SMU2
Elsewhere: RCSB PDB 6D63 · PDBe 6D63 · UniProt A0A0V8SMU2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.