MolNFT v1 · #145955 · protein
Apo crystal structure of terc, a terfestatin biosynthesis enzyme
6D34: “Apo crystal structure of terc, a terfestatin biosynthesis enzyme”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #145955 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6D34
- Type
- protein
- Length
- 263 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Terc
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Terc | protein | 132 | 36% helix, 45% strand | — |
| B | Terc | protein | 131 | 37% helix, 44% strand | — |
Ligands and binding sites
- IPA · Isopropyl alcohol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 259 | 0.74 | 0.87 | 35 | IPA |
| 2 | 216 | 0.73 | 0.88 | 30 | empty |
| 3 | 126 | 0.50 | 0.80 | 29 | empty |
| 4 | 120 | 0.48 | 0.79 | 27 | IPA |
Interfaces
1 interface between chains.
- A–B · 853 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 6D34 · Apo Crystal Structure of TerC, a Terfestatin Biosynthesis Enzyme · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6D34 · PDBe 6D34
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