MolNFT v1 · #145941 · protein
Crystal structure of the ferm domain of zebrafish FARP1
6D2Q · Ferm, rhogef (arhgef) and pleckstrin domain protein 1…: “Crystal structure of the ferm domain of zebrafish FARP1”. X-ray diffraction, 4 pockets (best druggability 0.66). MolNFT v1 #145941 on GenesisL1: 3D structure, binding sites…
- PDB
- 6D2Q
- Type
- protein
- Length
- 275 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferm, rhogef (arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
- UniProt
- E9QIC8
- Pockets
- 4 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferm, rhogef (arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) | protein | 275 | 39% helix, 27% strand | E9QIC8 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 424 | 0.66 | 0.79 | 52 | empty |
| 2 | 57 | 0.38 | 0.80 | 16 | empty |
| 3 | 57 | 0.34 | 0.78 | 13 | empty |
| 4 | 60 | 0.32 | 0.76 | 13 | empty |
Compared structures
- 6D2Q · Crystal structure of the FERM domain of zebrafish FARP1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E9QIC8
- Elsewhere: RCSB PDB 6D2Q · PDBe 6D2Q · UniProt E9QIC8
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