MolNFT v1 · #145919 · protein
Crystal structure of the ferm domain of zebrafish FARP2
6D21 · Ferm, rhogef and pleckstrin domain protein 2: “Crystal structure of the ferm domain of zebrafish FARP2”. X-ray diffraction, 2 pockets (best druggability 0.63). MolNFT v1 #145919 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6D21
- Type
- protein
- Length
- 280 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferm, rhogef and pleckstrin domain protein 2
- UniProt
- E7FE33
- Pockets
- 2 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferm, rhogef and pleckstrin domain protein 2 | protein | 280 | 41% helix, 26% strand | E7FE33 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 417 | 0.63 | 0.77 | 48 | empty |
| 2 | 62 | 0.37 | 0.79 | 16 | empty |
Compared structures
- 6D21 · Crystal structure of the FERM domain of zebrafish FARP2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E7FE33
- Elsewhere: RCSB PDB 6D21 · PDBe 6D21 · UniProt E7FE33
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