The arsenate respiratory reductase (arr) complex from shewanella sp. ana-3

Structure

x-ray diffraction · 3 distinct chains · 33% helix, 19% strand (DSSP).

Ligands and binding sites

• SF4 · Iron/sulfur cluster · ligand · 10 copies · chains A, B, C, D
• MGD · 2-amino-5,6-dimercapto-7-methyl-3,7,8A,9-tetrahydro-8-oxa-1,3,9,10-tetraaza-anthracen-4-one guanosine dinucleotide · ligand · 4 copies · chains A, C
• MO · Molybdenum atom · metal · 2 copies · chains A, C
• FMT · Formic acid · additive · 8 copies · chains A, B, C, D
• PG5 · 1-methoxy-2-[2-(2-methoxy-ethoxy]-ethane · additive · 2 copies · chains A, B, C, D
• PEG · Di(hydroxyethyl)ether · additive · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

12 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Interfaces

5 interfaces between chains.

• A–B · 3350 Ų buried · 55 hydrogen bonds · protein-protein
• C–D · 3246 Ų buried · 51 hydrogen bonds · protein-protein
• A–C · 342 Ų buried · 3 hydrogen bonds · protein-protein
• B–C · 223 Ų buried · 2 hydrogen bonds · protein-protein
• A–D · 67 Ų buried · 2 hydrogen bonds · protein-protein

Compared structures

• 6CZ7 · The arsenate respiratory reductase (Arr) complex from Shewanella sp. ANA-3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q7WTU0
• Every structure of UniProt Q7WTT9
• Elsewhere: RCSB PDB 6CZ7 · PDBe 6CZ7 · UniProt Q7WTU0 · UniProt Q7WTT9