MolNFT v1 · #145786 · protein
SA11 rotavirus NSP2 with disulfide bridge
6CY9 · Non-structural protein 2: “SA11 rotavirus NSP2 with disulfide bridge”. X-ray diffraction, 1 ligand (MG), 2 pockets (best druggability 0.71). MolNFT v1 #145786 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6CY9
- Type
- protein
- Length
- 310 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-structural protein 2
- EC
- 3.6.4.-
- UniProt
- A2T3N6
- Ligands
- MG
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Non-structural protein 2 (EC 3.6.4.-) | protein | 310 | 45% helix, 15% strand | A2T3N6 |
Ligands and binding sites
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 612 | 0.71 | 0.79 | 58 | empty |
| 2 | 147 | 0.48 | 0.78 | 21 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6CY9 · SA11 Rotavirus NSP2 with disulfide bridge · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2T3N6
- Elsewhere: RCSB PDB 6CY9 · PDBe 6CY9 · UniProt A2T3N6
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