MolNFT v1 · #145729 · protein
X-ray crystal structure of flavobacterium johnsoniae DIMANGANESE(II) ribonucleotide reductase beta subunit (aerobic)
6CWO: “X-ray crystal structure of flavobacterium johnsoniae DIMANGANESE(II) ribonucleotide reductase beta subunit…”. X-ray diffraction, 2 ligands (MN, MG), 9 pockets (best druggability 0.67). MolNFT v1 #145729 on GenesisL1: 3D structure…
- PDB
- 6CWO
- Type
- protein
- Length
- 611 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonucleotide reductase
- UniProt
- A5FCJ5
- Ligands
- MN, MG
- Pockets
- 9 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonucleotide reductase | protein | 307 | 72% helix, 0% strand | A5FCJ5 |
| B | Ribonucleotide reductase | protein | 304 | 71% helix, 0% strand | A5FCJ5 |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 4 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.67 | 0.94 | 30 | empty |
| 2 | 447 | 0.64 | 0.77 | 51 | empty |
| 3 | 406 | 0.63 | 0.77 | 49 | empty |
| 4 | 59 | 0.50 | 0.86 | 13 | empty |
| 5 | 62 | 0.43 | 0.82 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1244 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 6CWO · X-ray crystal structure of Flavobacterium johnsoniae dimanganese(II) ribonucleotide… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5FCJ5
- Elsewhere: RCSB PDB 6CWO · PDBe 6CWO · UniProt A5FCJ5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.