MolNFT v1 · #145655 · protein
Solution structure of the extraterminal (et) domain of BRD2
6CUI · Bromodomain-containing protein 2: “Solution structure of the extraterminal (et) domain of BRD2”. Solution nmr, 2 pockets (best druggability 0.31). MolNFT v1 #145655 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6CUI
- Type
- protein
- Length
- 132 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bromodomain-containing protein 2
- UniProt
- P25440
- Pockets
- 2 · best druggability 0.31
Structure
solution nmr · 1 distinct chain · 43% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bromodomain-containing protein 2 | protein | 132 | 43% helix, 0% strand | P25440 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 86 | 0.31 | 0.73 | 13 | empty |
| 2 | 55 | 0.27 | 0.73 | 13 | empty |
Compared structures
- 6CUI · Solution structure of the Extraterminal (ET) Domain of BRD2 · the same entry in another collection · chain A against A, TM-score 1.00
- P25440 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 2 (P25440) · a predicted model of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25440
- Elsewhere: RCSB PDB 6CUI · PDBe 6CUI · UniProt P25440
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