MolNFT v1 · #145529 · protein

Sediminispirochaeta smaragdinae sps-1 metallo-beta-lactamase

6CQS: “Sediminispirochaeta smaragdinae sps-1 metallo-beta-lactamase”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.63). MolNFT v1 #145529 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6CQS
Type: protein
Length: 242 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: E1R245
Ligands: ZN
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	242	32% helix, 28% strand	E1R245

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	223	0.63	0.82	22	ZN

Compared structures

6CQS · Sediminispirochaeta smaragdinae SPS-1 metallo-beta-lactamase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E1R245
Elsewhere: RCSB PDB 6CQS · PDBe 6CQS · UniProt E1R245

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.