MolNFT v1 · #145521 · protein
Crystal structure of mitochondrial single-stranded DNA binding proteins from S. cerevisiae, RIM1 (FORM1)
6CQK · Ssdna-binding protein essential for mitochondrial genome…: “Crystal structure of mitochondrial single-stranded DNA binding proteins from S. cerevisiae, RIM1 (FORM1)”. X-ray diffraction, 5 pockets (best druggability 0.65). MolNFT v1…
- PDB
- 6CQK
- Type
- protein
- Length
- 361 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ssdna-binding protein essential for mitochondrial genome maintenance
- UniProt
- A0A250WMX0
- Pockets
- 5 · best druggability 0.65
Structure
x-ray diffraction · 4 distinct chains · 11% helix, 58% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ssdna-binding protein essential for mitochondrial genome maintenance | protein | 93 | 9% helix, 58% strand | A0A250WMX0 |
| B | Ssdna-binding protein essential for mitochondrial genome maintenance | protein | 93 | 11% helix, 60% strand | A0A250WMX0 |
| C | Ssdna-binding protein essential for mitochondrial genome maintenance | protein | 88 | 11% helix, 57% strand | A0A250WMX0 |
| D | Ssdna-binding protein essential for mitochondrial genome maintenance | protein | 87 | 11% helix, 55% strand | A0A250WMX0 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.65 | 0.95 | 16 | empty |
| 2 | 354 | 0.60 | 0.77 | 42 | empty |
| 3 | 317 | 0.54 | 0.75 | 44 | empty |
| 4 | 77 | 0.38 | 0.78 | 16 | empty |
| 5 | 72 | 0.37 | 0.77 | 16 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1007 Ų buried · 31 hydrogen bonds · protein-protein
- A–B · 982 Ų buried · 30 hydrogen bonds · protein-protein
- A–D · 308 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 274 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 181 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6CQK · Crystal Structure of mitochondrial single-stranded DNA binding proteins from S.… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A250WMX0
- Elsewhere: RCSB PDB 6CQK · PDBe 6CQK · UniProt A0A250WMX0
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