MolNFT v1 · #145399 · protein

Solution NMR structure determination of mouse melanoregulin

6CMY: “Solution NMR structure determination of mouse melanoregulin”. Solution nmr, 2 pockets (best druggability 0.55). MolNFT v1 #145399 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6CMY
Type: protein
Length: 182 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Melanoregulin
UniProt: Q6NVG5
Pockets: 2 · best druggability 0.55

Structure

solution nmr · 1 distinct chain · 51% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Melanoregulin	protein	182	51% helix, 0% strand	Q6NVG5

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	138	0.55	0.82	23	empty
2	84	0.33	0.75	16	empty

Compared structures

6CMY · Solution NMR Structure Determination of Mouse Melanoregulin · the same entry in another collection · chain A against A, TM-score 1.00
Q6NVG5 · AlphaFold monomer V2.0 prediction for melanoregulin (Q6NVG5) · a predicted model of the same protein · chain A against A, TM-score 0.35

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6NVG5
Elsewhere: RCSB PDB 6CMY · PDBe 6CMY · UniProt Q6NVG5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.