MolNFT v1 · #145175 · protein
Crystal structure of human 17BETA-hsd type 1 in ternary complex with 2-meo-cc-156 and NADP+
6CGC: “Crystal structure of human 17BETA-hsd type 1 in ternary complex with 2-meo-cc-156 and NADP+”. X-ray diffraction, 2 ligands (NAP, F0A). MolNFT v1 #145175 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6CGC
- Type
- protein
- Length
- 555 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P14061
- Ligands
- NAP, F0A
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 278 | — | P14061 |
| B | — | protein | 277 | — | P14061 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 2 copies · chains A, B
- F0A · 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxy-2-methoxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6CGC · Crystal structure of human 17beta-HSD type 1 in ternary complex with 2-MeO-CC-156 and… · the same entry in another collection · chain A against A, TM-score 1.00
- P14061 · AlphaFold monomer V2.0 prediction for 17-beta-hydroxysteroid dehydrogenase type 1 (P14061) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14061
- Elsewhere: RCSB PDB 6CGC · PDBe 6CGC · UniProt P14061
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