MolNFT v1 · #145131 · protein

Proteus vulgaris higa antitoxin structure

6CF1 · Antitoxin higa: “Proteus vulgaris higa antitoxin structure”. X-ray diffraction, 1 ligand (K), 1 pocket (best druggability 0.43). MolNFT v1 #145131 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6CF1
Type: protein
Length: 186 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Antitoxin higa
UniProt: Q7A224
Ligands: K
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 2 distinct chains · 59% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Antitoxin higa	protein	92	59% helix, 0% strand	Q7A224
B	Antitoxin higa	protein	94	59% helix, 0% strand	Q7A224

Ligands and binding sites

K · Potassium ion · metal · 5 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	88	0.43	0.79	16	empty

Interfaces

1 interface between chains.

A–B · 1473 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

6CF1 · Proteus vulgaris HigA antitoxin structure · the same entry in another collection · chain A against A, TM-score 1.00
Q7A224 · AlphaFold monomer V2.0 prediction for antitoxin higa (Q7A224) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7A224
Elsewhere: RCSB PDB 6CF1 · PDBe 6CF1 · UniProt Q7A224

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