MolNFT v1 · #145060 · DNA

Hybrid-2 form human telomeric G quadruplex in complex with epiberberine

6CCW · DNA (26-mer): “Hybrid-2 form human telomeric G quadruplex in complex with epiberberine”. Solution nmr, 1 ligand (EWV), 1 pocket (best druggability 0.43). MolNFT v1 #145060 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6CCW
Type: DNA
Length: 26 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA (26-mer)
Ligands: EWV
Pockets: 1 · best druggability 0.43

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA (26-mer)	dna	26	—	—

Ligands and binding sites

EWV · Epiberberine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.43	0.78	11	EWV

Compared structures

6CCW · Hybrid-2 form Human Telomeric G Quadruplex in Complex with Epiberberine · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6CCW · PDBe 6CCW

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