MolNFT v1 · #144961 · protein

Transcriptional repressor, cour

6C9T: “Transcriptional repressor, cour”. X-ray diffraction, 3 pockets (best druggability 0.62). MolNFT v1 #144961 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6C9T
Type: protein
Length: 269 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cour
UniProt: Q6N8V9
Pockets: 3 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 75% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cour	protein	132	78% helix, 3% strand	Q6N8V9
B	Cour	protein	137	73% helix, 4% strand	Q6N8V9

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	138	0.62	0.85	25	empty
2	119	0.62	0.86	22	empty
3	59	0.31	0.76	14	empty

Interfaces

1 interface between chains.

A–B · 2696 Å² buried · 21 hydrogen bonds · protein-protein

Compared structures

6C9T · Transcriptional repressor, CouR · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6N8V9
Elsewhere: RCSB PDB 6C9T · PDBe 6C9T · UniProt Q6N8V9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.