MolNFT v1 · #144907 · protein
Directed evolutionary changes in kemp eliminase KE07 - crystal 23 round 6
6C8B: “Directed evolutionary changes in kemp eliminase KE07 - crystal 23 round 6”. X-ray diffraction, 6 pockets (best druggability 0.64). MolNFT v1 #144907 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6C8B
- Type
- protein
- Length
- 524 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kemp eliminase KE07
- Pockets
- 6 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Kemp eliminase KE07 | protein | 262 | 38% helix, 24% strand | — |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 344 | 0.64 | 0.79 | 46 | empty |
| 2 | 248 | 0.62 | 0.81 | 28 | empty |
| 3 | 246 | 0.51 | 0.75 | 28 | empty |
| 4 | 71 | 0.33 | 0.75 | 14 | empty |
| 5 | 51 | 0.32 | 0.77 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 489 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6C8B · Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6C8B · PDBe 6C8B
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