MolNFT v1 · #144814 · protein

N-terminal domain of helicobacter pylori LLAJI.R1

6C5D: “N-terminal domain of helicobacter pylori LLAJI.R1”. X-ray diffraction, 6 pockets (best druggability 0.42). MolNFT v1 #144814 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6C5D
Type: protein
Length: 504 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LLAJI.R1
UniProt: Q9ZMQ4
Pockets: 6 · best druggability 0.42

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	LLAJI.R1	protein	121	29% helix, 32% strand	Q9ZMQ4
D, B	LLAJI.R1	protein	131	25% helix, 35% strand	Q9ZMQ4

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	107	0.42	0.77	18	empty
2	96	0.39	0.76	17	empty
3	65	0.36	0.78	11	empty
4	69	0.34	0.76	16	empty
5	52	0.32	0.77	12	empty

Interfaces

3 interfaces between chains.

D–C · 898 Å² buried · 12 hydrogen bonds · protein-protein
A–B · 853 Å² buried · 6 hydrogen bonds · protein-protein
D–B · 41 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

6C5D · N-terminal domain of Helicobacter pylori LlaJI.R1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ZMQ4
Elsewhere: RCSB PDB 6C5D · PDBe 6C5D · UniProt Q9ZMQ4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.