MolNFT v1 · #144805 · protein
Ebola nucleoprotein nucleocapsid-like assembly and the asymmetric unit
6C54: “Ebola nucleoprotein nucleocapsid-like assembly and the asymmetric unit”. Electron microscopy, 10 pockets (best druggability 0.73). MolNFT v1 #144805 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6C54
- Type
- protein
- Length
- 720 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoprotein
- UniProt
- A0A1L7B8E4
- Pockets
- 10 · best druggability 0.73
Structure
electron microscopy · 2 distinct chains · 58% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoprotein | protein | 347 | 56% helix, 4% strand | A0A1L7B8E4 |
| B | Nucleoprotein | protein | 373 | 59% helix, 4% strand | A0A1L7B8E4 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.73 | 0.95 | 22 | empty |
| 2 | 82 | 0.54 | 0.84 | 24 | empty |
| 3 | 111 | 0.48 | 0.80 | 18 | empty |
| 4 | 51 | 0.47 | 0.85 | 11 | empty |
| 5 | 80 | 0.38 | 0.77 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 936 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 6C54 · Ebola nucleoprotein nucleocapsid-like assembly and the asymmetric unit · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1L7B8E4
- Elsewhere: RCSB PDB 6C54 · PDBe 6C54 · UniProt A0A1L7B8E4
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