MolNFT v1 · #1447 · protein
Glutamate dehydrogenase
1B26: “Glutamate dehydrogenase”. X-ray diffraction, 16 pockets (best druggability 0.85). MolNFT v1 #1447 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1B26
- Type
- protein
- Length
- 2,454 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamate dehydrogenase
- EC
- 1.4.1.3
- UniProt
- P96110
- Pockets
- 16 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Glutamate dehydrogenase (EC 1.4.1.3) | protein | 409 | 50% helix, 18% strand | P96110 |
Pockets
16 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1175 | 0.85 | 0.86 | 93 | empty |
| 2 | 1129 | 0.84 | 0.85 | 92 | empty |
| 3 | 1122 | 0.84 | 0.85 | 96 | empty |
| 4 | 1175 | 0.80 | 0.81 | 126 | empty |
| 5 | 1141 | 0.80 | 0.81 | 122 | empty |
Interfaces
12 interfaces between chains.
- B–E · 1053 Ų buried · 16 hydrogen bonds · protein-protein
- A–F · 1050 Ų buried · 17 hydrogen bonds · protein-protein
- C–D · 1022 Ų buried · 14 hydrogen bonds · protein-protein
- A–C · 906 Ų buried · 12 hydrogen bonds · protein-protein
- D–F · 893 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96110
- Elsewhere: RCSB PDB 1B26 · PDBe 1B26 · UniProt P96110
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