MolNFT v1 · #144628 · protein
Structure of S. cerevisiae ZIP2:SPO16 complex, P212121 form
6BZG · Protein ZIP2: “Structure of S. cerevisiae ZIP2:SPO16 complex, P212121 form”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.68). MolNFT v1 #144628 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BZG
- Type
- protein
- Length
- 387 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein ZIP2; Sporulation-specific protein 16
- UniProt
- P53061, P17122
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Protein ZIP2 | protein | 198 | 48% helix, 21% strand | P53061 |
| A | Sporulation-specific protein 16 | protein | 189 | 56% helix, 16% strand | P17122 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 207 | 0.68 | 0.86 | 30 | empty |
| 2 | 50 | 0.43 | 0.84 | 14 | empty |
| 3 | 74 | 0.37 | 0.77 | 14 | empty |
| 4 | 61 | 0.32 | 0.76 | 17 | empty |
| 5 | 58 | 0.30 | 0.75 | 21 | empty |
Interfaces
1 interface between chains.
- B–A · 2820 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 6BZG · Structure of S. cerevisiae Zip2:Spo16 complex, P212121 form · the same entry in another collection · chain B against B, TM-score 1.00
- P53061 · AlphaFold monomer V2.0 prediction for protein ZIP2 (P53061) · a predicted model of the same protein · chain B against A, TM-score 0.99
- P17122 · AlphaFold monomer V2.0 prediction for sporulation-specific protein 16 (P17122) · a predicted model of the same protein · chain A against A, TM-score 0.62
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53061
- Every structure of UniProt P17122
- Elsewhere: RCSB PDB 6BZG · PDBe 6BZG · UniProt P53061 · UniProt P17122
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