MolNFT v1 · #144626 · protein
Cryo-EM structure of BCL10 card filament
6BZE · B-cell LYMPHOMA/LEUKEMIA 10: “Cryo-EM structure of BCL10 card filament”. Electron microscopy, 16 pockets (best druggability 0.83). MolNFT v1 #144626 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BZE
- Type
- protein
- Length
- 848 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- B-cell LYMPHOMA/LEUKEMIA 10
- UniProt
- O95999
- Pockets
- 16 · best druggability 0.83
Structure
electron microscopy · 1 distinct chain · 61% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H | B-cell LYMPHOMA/LEUKEMIA 10 | protein | 106 | 61% helix, 0% strand | O95999 |
Pockets
16 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 322 | 0.83 | 0.93 | 55 | empty |
| 2 | 293 | 0.83 | 0.93 | 55 | empty |
| 3 | 342 | 0.83 | 0.92 | 59 | empty |
| 4 | 302 | 0.82 | 0.92 | 53 | empty |
| 5 | 705 | 0.81 | 0.85 | 59 | empty |
Interfaces
17 interfaces between chains.
- A–E · 554 Ų buried · 14 hydrogen bonds · protein-protein
- B–F · 549 Ų buried · 14 hydrogen bonds · protein-protein
- C–G · 549 Ų buried · 13 hydrogen bonds · protein-protein
- D–H · 543 Ų buried · 16 hydrogen bonds · protein-protein
- D–G · 435 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95999
- Elsewhere: RCSB PDB 6BZE · PDBe 6BZE · UniProt O95999
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.