MolNFT v1 · #144574 · protein
Crystal structure of toxoplasma gondii mitochondrial association factor 1 a (MAF1A)
6BXS: “Crystal structure of toxoplasma gondii mitochondrial association factor 1 a (MAF1A)”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.74). MolNFT v1 #144574 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6BXS
- Type
- protein
- Length
- 812 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mitochondrial association factor 1
- UniProt
- A0A193AUK9
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.74
Structure
x-ray diffraction · 3 distinct chains · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitochondrial association factor 1 | protein | 272 | 45% helix, 17% strand | A0A193AUK9 |
| B | Mitochondrial association factor 1 | protein | 270 | 41% helix, 17% strand | A0A193AUK9 |
| C | Mitochondrial association factor 1 | protein | 270 | 46% helix, 17% strand | A0A193AUK9 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 14 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.74 | 0.96 | 18 | empty |
| 2 | 221 | 0.63 | 0.82 | 28 | empty |
| 3 | 209 | 0.62 | 0.82 | 28 | empty |
| 4 | 257 | 0.56 | 0.77 | 38 | SO4 |
| 5 | 206 | 0.54 | 0.78 | 33 | empty |
Interfaces
2 interfaces between chains.
- A–B · 689 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 572 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6BXS · Crystal structure of Toxoplasma gondii Mitochondrial Association Factor 1 A (MAF1A) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A193AUK9
- Elsewhere: RCSB PDB 6BXS · PDBe 6BXS · UniProt A0A193AUK9
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