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MolNFT v1 · #144375 · protein

DDR1 bound to vx-680

6BRJ: “DDR1 bound to vx-680”. X-ray diffraction, 1 ligand (VX6). MolNFT v1 #144375 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6BRJ
Type: protein
Length: 274 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q08345
Ligands: VX6

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	274	—	Q08345

Ligands and binding sites

VX6 · Cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6BRJ · DDR1 bound to VX-680 · the same entry in another collection · chain A against A, TM-score 1.00
Q08345 · AlphaFold monomer V2.0 prediction for epithelial discoidin domain- containing receptor 1… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08345
Elsewhere: RCSB PDB 6BRJ · PDBe 6BRJ · UniProt Q08345

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