MolNFT v1 · #144340 · protein
Crystal structure of hepatis C virus protease (NS3) complexed with tripeptidic acyl sulfonamide inhibitor (compound 18)
6BQK: “Crystal structure of hepatis C virus protease (NS3) complexed with tripeptidic acyl sulfonamide inhibitor…”. X-ray diffraction, 2 ligands (Z1E, ZN). MolNFT v1 #144340 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BQK
- Type
- protein
- Length
- 386 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A075D220
- Ligands
- Z1E, ZN
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 193 | — | A0A075D220 |
Ligands and binding sites
- Z1E · N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-N-[(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-(difluoromethyl) cyclopropyl]-L-prolinamide · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6BQK · Crystal structure of hepatis C virus protease (NS3) complexed with tripeptidic acyl… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A075D220
- Elsewhere: RCSB PDB 6BQK · PDBe 6BQK · UniProt A0A075D220
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