MolNFT v1 · #144260 · protein

Eubacterium eligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate

6BO6 · Glycoside hydrolase family 2 candidate B-glucuronidase: “Eubacterium eligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate”. X-ray diffraction, 1 ligand (E0V), 5 pockets (best druggability 0.65). MolNFT v1 #144260 on…

PDB: 6BO6
Type: protein
Length: 493 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycoside hydrolase family 2 candidate B-glucuronidase
UniProt: C4Z6Z2
Ligands: E0V
Pockets: 5 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycoside hydrolase family 2 candidate B-glucuronidase	protein	493	21% helix, 27% strand	C4Z6Z2

Ligands and binding sites

E0V · 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	155	0.65	0.86	26	E0V
2	233	0.58	0.80	42	empty
3	192	0.49	0.76	25	empty
4	66	0.35	0.77	14	empty
5	50	0.32	0.77	15	empty

Compared structures

6BO6 · Eubacterium eligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C4Z6Z2
Elsewhere: RCSB PDB 6BO6 · PDBe 6BO6 · UniProt C4Z6Z2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.