MolNFT v1 · #144108 · protein

Human ABO(H) blood group glycosyltransferase gtb D302L mutant

6BJL · Abo blood group (transferase a, alpha 1-3-N…: “Human ABO(H) blood group glycosyltransferase gtb D302L mutant”. X-ray diffraction, 2 pockets (best druggability 0.62). MolNFT v1 #144108 on GenesisL1: 3D structure, binding sites and…

PDB: 6BJL
Type: protein
Length: 274 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Abo blood group (transferase a, alpha 1-3-N- acetylgalactosaminyltransferase transferase…
UniProt: D3HIC2
Pockets: 2 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Abo blood group (transferase a, alpha 1-3-N- acetylgalactosaminyltransferase transferase B, alpha 1-3- galactosyltransferase)	protein	274	34% helix, 20% strand	D3HIC2

Ligands and binding sites

GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	345	0.62	0.78	40	empty
2	58	0.28	0.74	16	empty

Compared structures

6BJL · Human ABO(H) blood group glycosyltransferase GTB D302L mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D3HIC2
Elsewhere: RCSB PDB 6BJL · PDBe 6BJL · UniProt D3HIC2

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