MolNFT v1 · #143998 · RNA
Hybrid NMR/CRYO-EM structure of the HIV-1 RNA dimerization signal
6BG9: “Hybrid NMR/CRYO-EM structure of the HIV-1 RNA dimerization signal”. Electron microscopy; solution nmr, 3 pockets (best druggability 0.58). MolNFT v1 #143998 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BG9
- Type
- RNA
- Length
- 94 nucleotides
- Chains
- 2
- Method
- electron microscopy; solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA dimerization signal
- Pockets
- 3 · best druggability 0.58
Structure
electron microscopy; solution nmr · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | RNA dimerization signal | rna | 47 | — | — |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 408 | 0.58 | 0.76 | 24 | empty |
| 2 | 303 | 0.54 | 0.76 | 19 | empty |
| 3 | 95 | 0.30 | 0.72 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2252 Ų buried · 246 hydrogen bonds · nucleic-nucleic
Compared structures
- 6BG9 · Hybrid NMR/CRYO-EM structure of the HIV-1 RNA dimerization signal · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6BG9 · PDBe 6BG9
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