MolNFT v1 · #143914 · protein
Crystal structure of human TAO3 kinase binding ADP
6BDN · SERINE/THREONINE-protein kinase TAO3: “Crystal structure of human TAO3 kinase binding ADP”. X-ray diffraction, 4 ligands (ADP, MG, PO4), 2 pockets (best druggability 0.68). MolNFT v1 #143914 on GenesisL1: 3D structure, binding sites…
- PDB
- 6BDN
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase TAO3
- EC
- 2.7.11.1
- UniProt
- Q9H2K8
- Ligands
- ADP, MG, PO4, SO4
- Pockets
- 2 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase TAO3 (EC 2.7.11.1) | protein | 307 | 45% helix, 17% strand | Q9H2K8 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- MG · Magnesium ion · metal · chains A
- PO4 · Phosphate ion · ion · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 504 | 0.68 | 0.79 | 58 | SO4, MG, ADP |
| 2 | 51 | 0.25 | 0.73 | 15 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H2K8
- Elsewhere: RCSB PDB 6BDN · PDBe 6BDN · UniProt Q9H2K8
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