MolNFT v1 · #143835 · protein
Crystal structure of frequency-interacting RNA helicase (frh)
6BB8 · Frq-interacting RNA helicase: “Crystal structure of frequency-interacting RNA helicase (frh)”. X-ray diffraction, 12 pockets (best druggability 0.83). MolNFT v1 #143835 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BB8
- Type
- protein
- Length
- 927 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Frq-interacting RNA helicase
- UniProt
- Q873J5
- Pockets
- 12 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Frq-interacting RNA helicase | protein | 927 | 46% helix, 13% strand | Q873J5 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 980 | 0.83 | 0.85 | 101 | empty |
| 2 | 443 | 0.76 | 0.85 | 69 | empty |
| 3 | 87 | 0.69 | 0.92 | 21 | empty |
| 4 | 91 | 0.65 | 0.90 | 17 | empty |
| 5 | 220 | 0.60 | 0.81 | 35 | empty |
Compared structures
- 6BB8 · Crystal Structure of Frequency-Interacting RNA helicase (FRH) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q873J5
- Elsewhere: RCSB PDB 6BB8 · PDBe 6BB8 · UniProt Q873J5
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