MolNFT v1 · #143815 · protein
Stigmatella aurantiaca phytochrome photosensory core module, wild type
6BAO · Photoreceptor-histidine kinase bphp: “Stigmatella aurantiaca phytochrome photosensory core module, wild type”. X-ray diffraction, 1 ligand (BLR), 16 pockets (best druggability 0.82). MolNFT v1 #143815 on GenesisL1: 3D structure…
- PDB
- 6BAO
- Type
- protein
- Length
- 1,006 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Photoreceptor-histidine kinase bphp
- UniProt
- Q097N3
- Ligands
- BLR
- Pockets
- 16 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Photoreceptor-histidine kinase bphp | protein | 503 | 34% helix, 24% strand | Q097N3 |
Ligands and binding sites
- BLR · 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1128 | 0.82 | 0.83 | 138 | BLR |
| 2 | 316 | 0.82 | 0.92 | 42 | BLR |
| 3 | 80 | 0.67 | 0.92 | 18 | empty |
| 4 | 567 | 0.62 | 0.75 | 55 | empty |
| 5 | 64 | 0.57 | 0.89 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1897 Ų buried · 23 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 6BAO · Stigmatella aurantiaca phytochrome photosensory core module, wild type · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q097N3
- Elsewhere: RCSB PDB 6BAO · PDBe 6BAO · UniProt Q097N3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.