MolNFT v1 · #143752 · protein
Crystals structure of B-RAF kinase domain in complex with an imidazopyridinyl benzamide inhibitor
6B8U: “Crystals structure of B-RAF kinase domain in complex with an imidazopyridinyl benzamide inhibitor”. X-ray diffraction, 1 ligand (8EN). MolNFT v1 #143752 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6B8U
- Type
- protein
- Length
- 501 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P15056
- Ligands
- 8EN
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 253 | — | P15056 |
| B | — | protein | 248 | — | P15056 |
Ligands and binding sites
- 8EN · ~{N}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6B8U · Crystals Structure of B-Raf kinase domain in complex with an Imidazopyridinyl benzamide… · the same entry in another collection · chain A against A, TM-score 1.00
- P15056 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase B-RAF (P15056) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15056
- Elsewhere: RCSB PDB 6B8U · PDBe 6B8U · UniProt P15056
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