GL1X · GenesisL1 explorer

MolNFT v1 · #143631 · protein

Structural basis for katanin self-assembly

6B5C · Katanin P60 ATPase-containing subunit a-like 1: “Structural basis for katanin self-assembly”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #143631 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6B5C
Type
protein
Length
293 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Katanin P60 ATPase-containing subunit a-like 1
EC
3.6.4.3
UniProt
Q9BW62
Pockets
2 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 59% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AKatanin P60 ATPase-containing subunit a-like 1 (EC 3.6.4.3)protein29359% helix, 10% strandQ9BW62

Ligands and binding sites

  • PG4 · Tetraethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11580.530.7924empty
21470.490.7830empty

Compared structures

  • 6B5C · Structural Basis for Katanin Self-Assembly · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9BW62 · AlphaFold monomer V2.0 prediction for katanin P60 ATPase-containing subunit a-like 1… · a predicted model of the same protein · chain A against A, TM-score 0.94

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