MolNFT v1 · #143574 · protein
The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin
6B3M: “The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with…”. X-ray diffraction, 3 ligands (NAG, MAN, BMA). MolNFT v1 #143574 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6B3M
- Type
- protein
- Length
- 5,542 residues
- Chains
- 24
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q5EP31, A0A182DWE1
- Ligands
- NAG, MAN, BMA
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E, G, K, Q, S | — | protein | 321 | — | Q5EP31 |
| B | — | protein | 174 | — | A0A182DWE1 |
| C, I, M, O, V, Y | — | protein | 214 | — | — |
| F, H, L, R, T | — | protein | 175 | — | A0A182DWE1 |
| P | — | protein | 213 | — | — |
| U, J, D, W, N | — | protein | 214 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 45 copies · chains A, B, D, E, G, K, R, I, M, O, Q, Y, S, F
- MAN · alpha-D-mannopyranose · sugar · 17 copies · chains C, I, M, O, Y, V
- BMA · beta-D-mannopyranose · sugar · 4 copies · chains M, Y, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6B3M · The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5EP31
- Every structure of UniProt A0A182DWE1
- Elsewhere: RCSB PDB 6B3M · PDBe 6B3M · UniProt Q5EP31 · UniProt A0A182DWE1
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