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MolNFT v1 · #143574 · protein

The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin

6B3M: “The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with…”. X-ray diffraction, 3 ligands (NAG, MAN, BMA). MolNFT v1 #143574 on GenesisL1: 3D structure, binding sites and pockets…

PDB
6B3M
Type
protein
Length
5,542 residues
Chains
24
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q5EP31, A0A182DWE1
Ligands
NAG, MAN, BMA

Structure

x-ray diffraction · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, E, G, K, Q, S—protein321—Q5EP31
B—protein174—A0A182DWE1
C, I, M, O, V, Y—protein214——
F, H, L, R, T—protein175—A0A182DWE1
P—protein213——
U, J, D, W, N—protein214——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 45 copies · chains A, B, D, E, G, K, R, I, M, O, Q, Y, S, F
  • MAN · alpha-D-mannopyranose · sugar · 17 copies · chains C, I, M, O, Y, V
  • BMA · beta-D-mannopyranose · sugar · 4 copies · chains M, Y, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6B3M · The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody… · the same entry in another collection · chain A against A, TM-score 1.00

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