MolNFT v1 · #143489 · protein
P21-activated kinase 1 in complex with a 4-azaindole inhibitor
6B16: “P21-activated kinase 1 in complex with a 4-azaindole inhibitor”. X-ray diffraction, 2 ligands (C7Y, SO4). MolNFT v1 #143489 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6B16
- Type
- protein
- Length
- 566 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13153
- Ligands
- C7Y, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 285 | — | Q13153 |
| B | — | protein | 281 | — | Q13153 |
Ligands and binding sites
- C7Y · N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)-N~2~-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6B16 · P21-activated kinase 1 in complex with a 4-azaindole inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
- Q13153 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak 1 (Q13153) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13153
- Elsewhere: RCSB PDB 6B16 · PDBe 6B16 · UniProt Q13153
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