MolNFT v1 · #143421 · RNA

RNA hairpin complex with guanosine dinucleotide ligand G(5')PPP(5')G

6AZ4 · RNA (32-mer): “RNA hairpin complex with guanosine dinucleotide ligand G(5')PPP(5')G”. X-ray diffraction, 1 ligand (GP3), 1 pocket (best druggability 0.26). MolNFT v1 #143421 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6AZ4
Type: RNA
Length: 41 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA (32-mer); RNA (5'-R(*CP*AP*GP*CP*AP*GP*CP*AP*G)-3')
Ligands: GP3
Pockets: 1 · best druggability 0.26

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (32-mer)	rna	32	—	—
B	RNA (5'-R(CPAPGPCPAPGPCPAP*G)-3')	rna	9	—	—

Ligands and binding sites

GP3 · Diguanosine-5'-triphosphate · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.26	0.71	12	empty

Interfaces

1 interface between chains.

A–B · 457 Å² buried · 40 hydrogen bonds · nucleic-nucleic

Compared structures

6AZ4 · RNA hairpin complex with guanosine dinucleotide ligand G(5')ppp(5')G · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6AZ4 · PDBe 6AZ4

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