MolNFT v1 · #143387 · protein

Structure of cathb with covalently linked compound 28

6AY2: “Structure of cathb with covalently linked compound 28”. X-ray diffraction, 1 ligand (C1G). MolNFT v1 #143387 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6AY2
Type: protein
Length: 509 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P07858
Ligands: C1G

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	255	—	P07858
B	—	protein	254	—	P07858

Ligands and binding sites

C1G · N~1~-[(2S)-1-amino-5-(carbamoylamino)pentan-2-yl]-N'~1~-[(1R)-1-(thiophen-3-yl)ethyl]cyclobutane-1,1-dicarboxamide · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6AY2 · Structure of CathB with covalently linked Compound 28 · the same entry in another collection · chain A against A, TM-score 1.00
P07858 · AlphaFold monomer V2.0 prediction for cathepsin B (P07858) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07858
Elsewhere: RCSB PDB 6AY2 · PDBe 6AY2 · UniProt P07858

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