MolNFT v1 · #143186 · protein
F9 pilus adhesin fmlh lectin domain from E. COLI UTI89 co-crystallized with ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside
6AS8 · Fml fimbrial adhesin fmld: “F9 pilus adhesin fmlh lectin domain from E. COLI UTI89 co-crystallized with ortho-biphenyl-2'-carboxyl…”. X-ray diffraction, 1 ligand (BTG), 1 pocket (best druggability 0.58). MolNFT v1 #143186 on…
- PDB
- 6AS8
- Type
- protein
- Length
- 306 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fml fimbrial adhesin fmld
- UniProt
- Q1RBS0
- Ligands
- BTG
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Fml fimbrial adhesin fmld | protein | 153 | 4% helix, 48% strand | Q1RBS0 |
Ligands and binding sites
- BTG · ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 384 | 0.58 | 0.75 | 55 | empty |
Interfaces
1 interface between chains.
- A–B · 501 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6AS8 · F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1RBS0
- Elsewhere: RCSB PDB 6AS8 · PDBe 6AS8 · UniProt Q1RBS0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.