MolNFT v1 · #143145 · DNA
Crystal structure of Z-DNA with 6-fold TWINNING_Z4A
6AQW · DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'): “Crystal structure of Z-DNA with 6-fold TWINNING_Z4A”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #143145 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6AQW
- Type
- DNA
- Length
- 48 nucleotides
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*CP*GP*CP*GP*CP*G)-3')
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') | dna | 6 | — | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 398 | 0.53 | 0.73 | 29 | empty |
| 2 | 244 | 0.48 | 0.75 | 18 | empty |
Interfaces
6 interfaces between chains.
- A–B · 324 Ų buried · 24 hydrogen bonds · nucleic-nucleic
- G–H · 323 Ų buried · 24 hydrogen bonds · nucleic-nucleic
- E–F · 323 Ų buried · 22 hydrogen bonds · nucleic-nucleic
- C–D · 323 Ų buried · 24 hydrogen bonds · nucleic-nucleic
- B–C · 120 Ų buried · 4 hydrogen bonds · nucleic-nucleic
Compared structures
- 6AQW · Crystal Structure of Z-DNA with 6-fold Twinning_Z4A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6AQW · PDBe 6AQW
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