MolNFT v1 · #143086 · protein

Crystal structure of lectin domain of F9 pilus adhesin fmlh from E. COLI UTI89

6AOW: “Crystal structure of lectin domain of F9 pilus adhesin fmlh from E. COLI UTI89”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.59). MolNFT v1 #143086 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6AOW
Type: protein
Length: 302 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: F9 pilus adhesin fmlh
UniProt: Q1RBS0
Ligands: SO4
Pockets: 1 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	F9 pilus adhesin fmlh	protein	152	5% helix, 49% strand	Q1RBS0
B	F9 pilus adhesin fmlh	protein	150	4% helix, 49% strand	Q1RBS0

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	390	0.59	0.76	55	empty

Interfaces

1 interface between chains.

A–B · 547 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

6AOW · Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1RBS0
Elsewhere: RCSB PDB 6AOW · PDBe 6AOW · UniProt Q1RBS0

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