MolNFT v1 · #143046 · protein

Crystal structure of human flash N-terminal domain

6ANO · CASP8-associated protein 2: “Crystal structure of human flash N-terminal domain”. X-ray diffraction. MolNFT v1 #143046 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ANO
Type: protein
Length: 145 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CASP8-associated protein 2
UniProt: Q9UKL3

Structure

x-ray diffraction · 2 distinct chains · 95% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	CASP8-associated protein 2	protein	70	94% helix, 0% strand	Q9UKL3
A	CASP8-associated protein 2	protein	75	96% helix, 0% strand	Q9UKL3

Interfaces

1 interface between chains.

B–A · 1862 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

6ANO · Crystal structure of human FLASH N-terminal domain · the same entry in another collection · chain B against B, TM-score 1.00
Q9UKL3 · AlphaFold monomer V2.0 prediction for CASP8-associated protein 2 (Q9UKL3) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UKL3
Elsewhere: RCSB PDB 6ANO · PDBe 6ANO · UniProt Q9UKL3

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