MolNFT v1 · #143030 · protein

Crystal structure of the nucelotide binding domain of an O-antigen polysaccharide ABC-transporter

6AN5 · ABC transporter: “Crystal structure of the nucelotide binding domain of an O-antigen polysaccharide ABC-transporter”. X-ray diffraction, 6 pockets (best druggability 0.81). MolNFT v1 #143030 on GenesisL1: 3D structure, binding sites…

PDB: 6AN5
Type: protein
Length: 451 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ABC transporter
UniProt: O67181
Pockets: 6 · best druggability 0.81

Structure

x-ray diffraction · 2 distinct chains · 41% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ABC transporter	protein	213	41% helix, 25% strand	O67181
B	ABC transporter	protein	238	42% helix, 24% strand	O67181

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1115	0.81	0.82	90	empty
2	179	0.68	0.86	24	empty
3	208	0.67	0.84	29	empty
4	138	0.47	0.78	29	empty
5	61	0.41	0.81	18	empty

Interfaces

1 interface between chains.

A–B · 1242 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

6AN5 · Crystal Structure of The Nucelotide Binding Domain of an O-antigen polysaccharide… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O67181
Elsewhere: RCSB PDB 6AN5 · PDBe 6AN5 · UniProt O67181

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